Zsuzsanna Helyes Selected Research

somatostatin receptor subtype-4

12/2019	Novel Drug-Like Somatostatin Receptor 4 Agonists are Potential Analgesics for Neuropathic Pain.
1/2018	Role of Transient Receptor Potential Ankyrin 1 Ion Channel and Somatostatin sst4 Receptor in the Antinociceptive and Anti-inflammatory Effects of Sodium Polysulfide and Dimethyl Trisulfide.
8/2009	Impaired defense mechanism against inflammation, hyperalgesia, and airway hyperreactivity in somatostatin 4 receptor gene-deleted mice.
1/2008	Inhibitory effects of synthetic somatostatin receptor subtype 4 agonists on acute and chronic airway inflammation and hyperreactivity in the mouse.
6/2006	Analgesic effects of the somatostatin sst4 receptor selective agonist J-2156 in acute and chronic pain models.

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Zsuzsanna Helyes Research Topics

Disease

54	Inflammation (Inflammations) 06/2022 - 05/2004
41	Hyperalgesia 05/2022 - 08/2002
39	Pain (Aches) 03/2022 - 09/2004
21	Arthritis (Polyarthritis) 05/2022 - 05/2004
14	Edema (Dropsy) 01/2019 - 05/2007
13	Migraine Disorders (Migraine) 02/2022 - 01/2012
11	Neurogenic Inflammation 11/2020 - 08/2002
9	Neuralgia (Stump Neuralgia) 06/2021 - 09/2003
8	Pneumonia (Pneumonitis) 06/2022 - 01/2008
7	Rheumatoid Arthritis 03/2022 - 10/2014
7	Hypersensitivity (Allergy) 02/2021 - 08/2009
7	Colitis 03/2019 - 09/2010
5	Body Weight (Weight, Body) 05/2022 - 01/2016
5	Chronic Pain 03/2022 - 06/2006
5	Headache (Headaches) 10/2021 - 01/2012
5	Bronchial Hyperreactivity 06/2020 - 05/2007
5	Hyperplasia 02/2015 - 05/2007
4	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 03/2019 - 09/2010
3	Squamous Cell Carcinoma of Head and Neck 04/2022 - 09/2020
3	Chronic Obstructive Pulmonary Disease (COPD) 04/2022 - 10/2017
3	Complex Regional Pain Syndromes 03/2022 - 02/2014
3	Neuroinflammatory Diseases 02/2022 - 04/2020
3	Reperfusion Injury 01/2021 - 04/2011
3	Dermatitis 01/2016 - 12/2005
3	Allergic Contact Dermatitis 01/2016 - 12/2005
3	Ischemia 04/2011 - 11/2010
2	Fibromyalgia (Fibrositis) 03/2022 - 01/2022
2	Neoplasms (Cancer) 02/2022 - 01/2021
2	Hypotension (Low Blood Pressure) 01/2022 - 07/2005
2	Skin Diseases (Skin Disease) 01/2022 - 01/2016
2	Atrophy 10/2021 - 04/2011
2	Diabetic Neuropathies (Diabetic Neuropathy) 10/2021 - 09/2004
2	Diabetes Complications 02/2021 - 03/2016
2	Hyperglycemia 02/2021 - 03/2016
2	Wounds and Injuries (Trauma) 01/2021 - 02/2014
2	Visceral Pain 01/2021 - 10/2016

Drug/Important Bio-Agent (IBA)

26	Capsaicin (Zostrix)FDA Link 01/2022 - 05/2004
20	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 03/2022 - 01/2009
18	NeuropeptidesIBA 10/2021 - 08/2002
18	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2021 - 08/2002
14	Analgesics (Analgesic Drugs)IBA 01/2022 - 05/2004
13	Peroxidase (Myeloperoxidase)IBA 06/2022 - 05/2007
11	Pharmaceutical PreparationsIBA 01/2022 - 01/2018
11	resiniferatoxinIBA 02/2021 - 09/2003
10	CytokinesIBA 06/2022 - 10/2010
10	AnkyrinsIBA 02/2022 - 01/2016
8	EndotoxinsIBA 06/2022 - 05/2007
8	Freund's AdjuvantIBA 01/2022 - 05/2004
8	Substance PIBA 01/2021 - 06/2007
8	TachykininsIBA 01/2020 - 10/2010
7	CarrageenanIBA 01/2018 - 10/2005
7	TRPV1 receptorIBA 10/2017 - 07/2005
6	Ion Channels (Ion Channel)IBA 05/2022 - 01/2017
6	SmokeIBA 04/2022 - 04/2016
6	AutoantibodiesIBA 03/2022 - 02/2014
6	Formaldehyde (Formol)FDA Link 01/2018 - 09/2004
6	Peptides (Polypeptides)IBA 01/2018 - 10/2010
5	Immunoglobulin G (IgG)IBA 03/2022 - 02/2014
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 08/2009
5	Streptozocin (Streptozotocin)FDA Link 10/2021 - 09/2004
5	LipopolysaccharidesIBA 06/2020 - 05/2007
5	hemokinin-1IBA 04/2020 - 01/2013
5	somatostatin receptor subtype-4IBA 12/2019 - 06/2006
4	Messenger RNA (mRNA)IBA 05/2022 - 12/2009
4	Proteins (Proteins, Gene)FDA Link 02/2021 - 09/2015
4	Amine Oxidase (Copper-Containing)IBA 02/2021 - 01/2017
4	Calcitonin Gene-Related PeptideIBA 01/2021 - 06/2007
4	GTP-Binding Proteins (G-Protein)IBA 01/2020 - 11/2006
4	TT2-32IBA 01/2008 - 08/2002
3	Blood Glucose (Blood Sugar)IBA 10/2021 - 03/2016
3	Antidepressive Agents (Antidepressants)IBA 10/2020 - 01/2017
3	LigandsIBA 01/2020 - 01/2016
3	Opioid Analgesics (Opioids)IBA 01/2020 - 10/2016
3	LipidsIBA 01/2020 - 05/2015
3	Dextrans (Dextran)FDA Link 01/2019 - 01/2014
3	Matrix Metalloproteinases (MMPs)IBA 01/2019 - 03/2015
3	incobotulinumtoxinA FDA Link 01/2019 - 01/2016
3	Acetic Acid (Vinegar)FDA LinkGeneric 10/2016 - 06/2007
3	Dextran SulfateIBA 01/2016 - 09/2010
3	GalaninIBA 01/2016 - 01/2015
3	OxazoloneIBA 01/2016 - 08/2009
3	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 05/2014 - 10/2010
2	AntibodiesIBA 03/2022 - 01/2022
2	Janus Kinase InhibitorsIBA 01/2022 - 01/2022
2	Phenobarbital (Luminal)FDA Link 01/2022 - 01/2021
2	TRPV Cation ChannelsIBA 01/2022 - 12/2005
2	CalciumIBA 06/2021 - 01/2017
2	Insulin (Novolin)FDA Link 02/2021 - 10/2016
2	CreatinineIBA 02/2021 - 03/2016
2	EnzymesIBA 02/2021 - 01/2021
2	Retinaldehyde (Retinal)IBA 02/2021 - 03/2016
2	Peptide Hydrolases (Proteases)FDA Link 01/2021 - 02/2016
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2006
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2021 - 01/2021

Therapy/Procedure

15	Therapeutics 04/2022 - 10/2005
10	Ligation 11/2020 - 09/2003
4	Oral Administration 11/2020 - 05/2014
3	Subcutaneous Injections 01/2022 - 05/2004
3	Injections 02/2021 - 01/2016
2	Drug Therapy (Chemotherapy) 04/2022 - 01/2017